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Spectrophotometric determination of some benzothiadiazine diuretics with 7,7,8,8-tetracyanoquinodimethane
Authors:Mohamed A M
Affiliation:Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Abstract:A new spectrophotometric method for the determination of some benzothiadiazine drugs is presented, based on reaction with 7,7,8,8-tetracyanoquinodimethane in sodium acetate medium and measurement at 578 nm. Beer's law is obeyed in the concentration range 0.7-6.0 mug/ml for all eight drugs tested.
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