| Study on the Synthesis of Metabolite CM2 of Clausenamide |
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| 作者姓名： | XingZhouLI KeMeiWU LiangHUANG |
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| 作者单位： | InstituteofMateriaMedica,ChineseAcademyofMedicalSciences＆PekingUnionMedicalCollege,Beijing100050 |
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| 基金项目： | This work was supported by the National Natural Science Foundation of China. ( No.29790121) |
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| 摘 要： | Synthesis of the optically active metabolite of clausenamide cm2(3,5-dihydroxy-5-(α-hydroxylbenzyl)-1-methyl-4-benzylpyrrolidin-2-one)from 3-O-acetyl-clausenamide was described.
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| 关 键 词： | 代谢物 合成 CM1 CM2 羟基苯 脱酰化作用 吡咯烷酮 |
Study on the Synthesis of Metabolite CM2 of Clausenamide |
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| XingZhouLI KeMeiWU LiangHUANG.Study on the Synthesis of Metabolite CM2 of Clausenamide[J].Chinese Chemical Letters,2003,14(4):338-340. |
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| Authors: | Xing Zhou LI Ke Mei WU Liang HUANG |
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| Abstract: | Synthesis of the optically active metabolite of clausenamide CM2 (3, 5-dihydroxy- 5-(a-hydroxylbenzyl)-1-methyl-4-benzylpyrrolidin-2-one) from 3-O-acetyl- clausenamide was described. |
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| Keywords: | Metabolite clausenamide dehydration dihydroxylation deacylation |
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