An activity-based fluorogenic probe for sensitive and selective monoamine oxidase-B detection |
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| Authors: | Long Shaobo Chen Lin Xiang Yumi Song Minggui Zheng Yuguo Zhu Qing |
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| Affiliation: | Institute of Bioengineering, Zhejiang University of Technology, Chaowang Road 18, China. |
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| Abstract: | We report the design and synthesis of a new class of fluorogenic probes based on monoamine oxidase-triggered oxidative C-O bond cleavage. The selectivity of probe P1 towards MAO-B was 22-fold higher than that towards MAO-A. |
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