A rapid and facile signal enhancement method for microcantilever-based immunoassays using the agglomeration of ferromagnetic nanoparticles |
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| Authors: | Lee Dongkyu Kwon Donghoon Ko Wooree Joo Jinmyoung Seo Hyejung Lee Soo Suk Jeon Sangmin |
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| Affiliation: | Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Korea. |
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| Abstract: | A rapid and facile signal enhancement method for detecting alpha-fetoprotein (AFP) was developed using the magnetic agglomeration of ferromagnetic nanoparticles and microcantilever sensors. The resonance frequency and deflection of the cantilevers were found to be more than 10-fold greater than that before physical agglomeration of the free nanoparticles around the magnetized nanoparticles. |
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