Microwave assisted catalyst-free synthesis of azaarene-substituted 3-hydroxy-2-oxindoles by the functionalization of sp C-H bond in methyl pyridine |
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| Authors: | H.M. Meshram N. Nageswara RaoL. Chandrasekhara Rao N. Satish Kumar |
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| Affiliation: | Natural Products Chemistry Division, Indian Institute of Chemical Technology, Hyderabad 500 007, India |
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| Abstract: | A highly efficient synthesis of azaarene-substituted 3-hydroxy-2-oxindoles in catalyst-free conditions is described by the reaction of 2-methyl pyridines with isatins under microwave irradiation in aqueous medium. Simple reaction conditions, high yields of the products and environmentally benign medium are attractive features of the present protocol. |
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| Keywords: | Catalyst free conditions Isatin Methyl pyridine Microwave Water |
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