| THE THREE-DIMENSIONAL STRUCTURE OF TRICHOSANTHIN MOLECULE |
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| 作者姓名： | 潘克桢 林玉娟 傅珠玑 周康靖 蔡兆平 陈志伟 张永茂 董贻诚 吴伸 马星奇 王耀萍 陈世芝 王家槐 张学军 倪朝周 张志明 夏宗芗 范肇昌 田庚元 |
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| 作者单位： | Fujian Institute of Research on the Structure of Matter，Academia Sinica，Fuzhou，Fujian Institute of Research on the Structure of Matter，Academia Sinica，Fuzhou，Fujian Institute of Research on the Structure of Matter，Academia Sinica，Fuzhou，Fujian Institute of Research on the Structure of Matter，Academia Sinica，Fuzhou，Fujian Institute of Research on the Structure of Matter，Academia Sinica，Fuzhou，Fujian Institute of Research on the Structure of Matter，Academia Sinica，Fuzhou，Fujian Institute of Research on the Structure of Matter，Academia Sinica，Fuzhou，Institute of Biophysics，Academia Sinica，Beijing，Institute of Biophysics，Academia Sinica，Beijing，Institute of Biophysics，Academia Sinica，Beijing，Institute of Biophysics，Academia Sinica，Beijing，Institute of Biophysics，Academia Sinica，Beijing，Institute of Biophysics，Academia Sinica，Beijing，Institute of Biophysics，Academia Sinica，Beijing，Shanghai Institute of Organic Chemistry，Academia Sinica，Shanghai Institute of Organic Chemistry，Academia Sinica，Shanghai Institute of Organic Chemistry，Academia Sinica，Shanghai Institute of Organic Chemistry，Academia Sinica，Shanghai Institute of Organic Chemistry，Academia Sinica |
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| 摘 要： | A model completed recently of two trichosanthin molecules in an asymmetric unit belonging to themonoclinic system is reported. It can be seen that the molecular, structure consists of two domains, onelarge and one small, and that there are some features in the secondary structure. The dissimilarity be-tween two molecules as well as their interactions in an independent unit rorrelated in a non-symmetricway has been described. moreover, the binding sites of the heavyatom position in the derivatives are alsodiscussed.
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