| A New Hybrid Model of Amino Acid Substitution for Protein Functional Classification |
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| 作者姓名： | Ke Long WANG Zhi Ning WEN Fu Sheng NIE Meng Long LI |
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| 作者单位： | [1]College of Chemistry, Sichuan University, Chengdu 610064 [2]State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, Changsha 410082 |
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| 摘 要： | In recent years, methods of protein sequences analysis have been gradually evolved into two directions: One is based on the models of probability and statistics1-4; the other is based on the digital signal processing technologies 5-8. The latter mainly converts the protein character sequences into digital signals and uses some signal processing methods to analyze them, i.e., fast Fourier transform (FFT). However, it is still unsolved how to characterize the protein sequences accurately with …
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| 关 键 词： | 氨基酸 混合模型 代入法 蛋白质 天然化合物 |
| 收稿时间： | 2004-09-06 |
A New Hybrid Model of Amino Acid Substitution for Protein Functional Classification |
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| Ke Long WANG Zhi Ning WEN Fu Sheng NIE Meng Long LI.A New Hybrid Model of Amino Acid Substitution for Protein Functional Classification[J].Chinese Chemical Letters,2005,16(8):1133-1136. |
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| Authors: | Ke;Long;WANG;Zhi;Ning;WEN;Fu;Sheng;NIE;Meng;Long;LI |
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| Abstract: | In this paper, a new hybrid model of amino acid substitution is developed and compared with the others in previous works. The results show that the new hybrid model can characterize the protein sequences very well by calculating Fisher weights, which can denote how much the variants contribute to the classification. |
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| Keywords: | Hybrid model of amino acid substitution protein functional classification Fisher weights |
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