Alkaloid-rich plant Tylophora indica; current trends in isolation strategies,chemical profiling and medicinal applications |
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Institution: | 1. Department of Botany, University of Sargodha, Sargodha 40100, Pakistan;2. Department of Chemistry, University of Sargodha, Sargodha 40100, Pakistan;3. Department of Chemistry, GC University Lahore, Lahore 54000, Pakistan;4. Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Aljouf, Sakaka 2014, Saudi Arabia |
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Abstract: | Tylophora indica, a threatened medicinal plant of family Asclepiadaceae, grows profoundly in Asia, Africa, Australia, Oceanic Islands, Ceylon, Malay island, and Borneo. The plant is a twinning herb that is excessively used in folk medicine as a substitute of ipecac, an expectorant. Different parts of the plant are accredited for the anti-asthmatic, antibacterial, anti–psoriasis, antimicrobial, antiulcer, antiallergic, antidiarrhoeal, hypolipidemic, and anxiolytic properties. Antidiabetic, hepatoprotective, antiangiogenic, anti-tumor, antioxidant, anticonvulsant, anti-rheumatic, and diuretic activities are also attributed to the magnificent medicinal plant owing to the occurrence of various active phytochemicals such as alkaloids, saponins, phytosterols, tannins, and primary metabolites. The plant has been exploited by the ethnic people due to the immense medicinal importance, leading to the endangerment of the plant species. The review brings to light the important pharmacological attributes, folk medicinal uses, and biotechnological approaches that must be followed to save the plant from extinction. |
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Keywords: | Endangered species Phytochemistry Toxicity Folk medicinal uses Pharmacological attributes |
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