| Abstract: | “Direct Analysis of Daughter Ions” (DADI) can be carried out with commercial mass spectrometers embodying the Nier-Johnson inverse geometry. DADI measurements permit experimental detection of the consecutive formation of molecule fragments (fragment genesis). Knowledge of fragment genesis enables the chemist to clarify the fragmentation processes of molecule-ions and provides information on the structure of fragments formed in the mass spectrometer. In combination with classical mass spectrometry such information makes it easier to determine the structure of compounds, to analyze mixtures, to determine the sequence in periodically constructed molecules, for example oligopeptides, and to study rearrangement reactions occurring in the mass spectrometer. |
