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Solvolysis of 2-Amino-2-thiazoline Derivatives by Aliphatic Amino Alcohols
Authors:A. A. Mandrugin  V. M. Fedoseev  O. V. Dubovaya  A. A. Rodyunin  M. N. Semenko
Affiliation:(1) M. V. Lomonosov Moscow State University, 119899 Moscow, Russia
Abstract:The opening of the thiazoline ring upon the action of amino alcohols was studied. The effects of the reagent ratio and structures of the heterocycles and amino alcohols on aminolysis were investigated. A new method was developed for the preparative synthesis of a series of N'-(hydroxyalkyl)-2-guanidinoalkanethiols.
Keywords:N'-(hydroxyalkyl)-2-guanidinoalkanethiols  2-amino-2-thiazoline derivatives  solvolysis
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