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Organocatalyzed Synthesis of Functionalized Quinolines
Authors:Lian‐Hua Li  Zhi‐Jie Niu  Yong‐Min Liang
Abstract:As one of the most widely investigated compound skeleton, quinolines possess important medicinal and biological activities. As such, a great number of literatures, including reviews, have reported various methodologies to construct quinolines. Recently, organocatalyzed reactions have attracted the attention of organic chemists due to its being “green” because the reactions avoid the use of toxic metals. In this review, various distinctive contributions are surveyed with specific emphasis on organocatalyzed reactions for quinoline core constructions.
Keywords:metal-free approach  organocatalysis  quinolines  synthetic methods
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