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Polysaccharide Based Hemostatic Strategy for Ultrarapid Hemostasis
Authors:Yeyi Chen  Lei Wu  Pengpeng Li  Xiao Hao  Xiao Yang  Guanghui Xi  Wen Liu  Yakai Feng  Hongchao He  Changcan Shi
Abstract:Bleeding complications usually cause significant morbidity and mortality in civilian and military populations. In clinical application, hemostatic sponges, gauzes, hydrogel, and bandages are widely used as the traditional effective hemostatic products for hemorrhage. However, the traditional hemostatic devices or agents cannot meet the requirement for treatment of massive bleeding. Therefore, the excellent hemostatic performance of hemostatic products are of great significance for saving lives. Natural polysaccharides, as the main chemical component, have been widely used in the preparation of hemostasis due to their perfect biocompatibility and biodegradability. Polysaccharide based hemostatic products are available in variety of forms, such as, hydrogel, sponges, gauze and microspheres. The purpose of the present review is to report the research progress on polysaccharide hemostatic products and technology.
Keywords:hemostasis  hemostatic strategy  performance  polysaccharides
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