| Abstract: | 3-(2-Di-n-propylaminoethyl)pyrrole (1a) was prepared in good yield by reduction of pyrrole-3-(N,N-di-n-propylglyoxamide) (9) with lithium aluminum hydride. 3-(2-Di-n-propylaminoethyl)-5-acetylpyrrole (1b) was prepared by first acetylation of 1-p-toluenesulfonyl-3-(2-di-n-propylaminoethyl)pyrrole (6) followed by hydrolysis of the p-toluenesulfonyl substituent. The starting material 6 was prepared by homologation of 1-(p-toluenesulfonyl)pyrrole-3-carboxaldehyde (3) to the corresponding acetaldehyde followed by reductive amination of the latter. |
