Coupling micro-LC and capillary GC as a powerful tool for the analysis of complex mixtures

A multidimensional chromatography system with a packed fused silica Micro-LC column connected on-line with capillary gas chromatography is presented. The Micro-LC column is used for group separation. Whole peaks are injected into the capillary GC column via an on-column injector. The reproducibility of the proposed transfer system for polyaromatic hydrocarbons is 3% to 7% relative standard deviation. The potential of this on-line Micro-LC-GC system is demonstrated by the analyses of PAH's and of a complex light gasoline fraction.