A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue |
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Authors: | Masanta Goutam Heo Cheol Ho Lim Chang Su Bae Sung Keun Cho Bong Rae Kim Hwan Myung |
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Institution: | Division of Energy Systems Research and Molecular Science & Technology Research Center, Ajou University, Suwon, 443-749, Korea. |
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Abstract: | We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H(2)O(2) in live cells and intact tissues at >100 μm depth through the use of two-photon microscopy. |
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