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色谱技术在中药有效成分辨识中的应用进展
引用本文:李绍平,赵静,钱正明,李静. 色谱技术在中药有效成分辨识中的应用进展[J]. 中国科学:化学, 2010, 0(6): 651-667
作者姓名:李绍平  赵静  钱正明  李静
作者单位:澳门大学中华医药研究院,澳门
基金项目:国家自然科学基金(30928033); 澳门特别行政区科学技术发展基金(028/2006/A2); 澳门大学研究基金(UL015/09-Y1)资助
摘    要:中药效应成分辨识是中药质量控制研究的关键,本文从化学特性、生物靶标和整体作用三个层面综述了2000年以来色谱技术在中药效应成分辨识研究中的应用进展,并提出未来发展方向.

关 键 词:色谱  中药  质量控制  效应成分

Advanced development of chromatography in screening and identification of effective compounds in Chinese materia medica
LI ShaoPing,ZHAO Jing,QIAN ZhengMing & LI Jing. Advanced development of chromatography in screening and identification of effective compounds in Chinese materia medica[J]. Scientia Sinica Chimica, 2010, 0(6): 651-667
Authors:LI ShaoPing  ZHAO Jing  QIAN ZhengMing & LI Jing
Affiliation:Institute of Chinese Medical Sciences,University of Macau,Macao SAR,China
Abstract:Screening and identification of effective compounds in Chinese materia medica is the key for its quality control,which is critical for ensuring the safety and efficacy in clinic.Herein,the advanced development of chromatography in screening and identification of effective compounds in Chinese materia medica since 2000 was reviewed based on the strategies of chemical characteristics,drug targets and integrating chemical analysis and pharmacological assay.The prospect of chromatography in this field was also discussed.
Keywords:chromatography  Chinese materia medica  quality control  effective compounds
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