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无创血液成分检测全波段信号信噪比均衡
作者姓名:Li G  Wang HQ  Zhang H  Lin L  Wu XR  Zhang BJ
作者单位:天津大学精密测试技术及仪器国家重点实验室;天津师范大学物理与电子信息学院
基金项目:国家自然科学基金项目(30973964,60674111);天津市应用基础及前沿技术研究计划项目(11JCZDJC17100,10JCYBJC00400)资助
摘    要:为充分扩展动态光谱无创检测血液成分的种类和提高检测精度,在全波段范围内对光源、组织吸收和传感器的灵敏度进行统筹考虑,通过光源补偿和加入远心透镜设计不仅扩大了有效光谱检测范围,而且均衡了全波段范围光电脉搏波信噪比,提高了动态光谱信号整体信噪比并扩大了测量带宽。动态光谱质量评估的方法验证了该方法的有效性:将可见动态光谱的有效检测范围从600~1000nm拓宽到500~1135nm,近红外动态光谱的有效检测范围从900~1 100nm拓宽到900~1 700nm,既为基于动态光谱无创检测新的血液成分创造了条件,也可进一步提高已可检测血液成分的精度。

关 键 词:动态光谱  信噪比  均衡  无创检测  光谱分析

Equalization of whole-band signal's SNR in the blood components noninvasive measurement
Li G,Wang HQ,Zhang H,Lin L,Wu XR,Zhang BJ.Equalization of whole-band signal's SNR in the blood components noninvasive measurement[J].Spectroscopy and Spectral Analysis,2012,32(2):486-490.
Authors:Li Gang  Wang Hui-quan  Zhang Hao  Lin Ling  Wu Xiao-rong  Zhang Bao-ju
Institution:State Key Laboratory of Precision Measurement Technology and Instruments, Tianjin University, Tianjin 300072, China. ligang59@tju.edu.cn
Abstract:To fully extend the category of blood components that can be noninvasively measured by dynamic spectrum (DS) method and to increase its measuring precision, an overall consideration of light source, tissue absorption and sensor's sensitivity was made. Compensating the light source and adding the telecentric lens not only expand the spectral effective detecting range, but also balance the signal-to-noise ratio (SNR) of the photoelectric pulse in the whole band equalization. The integral SNR of DS signal was increased and the measurement bandwidth was expanded. The effectiveness of this method was validated by the quality evaluation criterion of DS data: the effective detecting range of visible DS was widened from 600-1 000 nm to 500-1 135 nm; the effective detecting range of near-infrared DS was widened from 900-1 100 nm to 900-1 700 nm. The results show that the design can create the condition for detection of new blood components noninvasively, and enhance the prediction accuracy of the blood components, for which noninvasive measuring using DS method has been achieved.
Keywords:Dynamic spectrum  Signal-to-noise ratio  Noninvasive measuring  Equalization  Spectral analysis
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