Reaction of carbonyl compounds with diazoalkanes as a method for epoxide synthesis. A review

The application of the reaction of carbonyl compounds with diazoalkanes the preparation of epoxides is reviewed. The effects of the structures of the reagent and substrate and of the solvent on the reaction course and product yield are examined. The stereochemistry of epoxide formation is discussed.Belorus State Technological University, 220630 Minsk. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 291–309, March, 1995. Original article submitted July 29, 1994.