脂肪醇氨氧化反应制备脂肪腈研究进展北大核心CSCD

脂肪腈是一类非常重要的化工原料和中间体,被广泛应用于医药、农用化学品、染料和合成树脂等领域.在诸多合成脂肪腈的路线中,脂肪醇氨氧化制备脂肪腈的路线使用可源于生物质资源的脂肪醇为原料,有助于“碳中和”和“碳达峰”目标的实现;同时,该反应副产物为水或氢气,符合“绿色”可持续发展的要求,具有重要的研究价值.根据脂肪醇氨氧化制备脂肪腈的过程中是否需要向体系中提供氧气,氨氧化过程可分为需氧氧化-氨化反应和脱氢氧化-氨化反应两类.需氧氧化-氨化反应在均相催化体系和非均相催化体系中均具有相关研究,而脱氢氧化-氨化反应的研究则主要集中在非均相体系中.按照以上分类,综述了脂肪醇氨氧化制备脂肪腈催化体系的研究进展,分析了不同种类催化体系的优势与尚存在的不足,并展望了该反应催化体系未来发展的方向.

Research Progress on Preparation of Aliphatic Nitriles by Ammonia Oxidation of Aliphatic Alcohols

Aliphatic nitriles are extremely important chemical raw materials and intermediates, which are widely used in the areas of medicine, agricultural chemicals, dyes and synthetic resins. Among the routes for the synthesis of aliphatic nitriles, ammoxidation of aliphatic alcohol method is a green route to prepare aliphatic nitriles, thus has great research significance. On the one hand, the raw materials for the route are aliphatic alcohols derived from biomass resources, which will contribute to achieve the goals of '' carbon neutrality '' and '' carbon peak '', on the other hand, the byproduct of the reaction is water or hydrogen, which meets the requirements of '' green '' sustainable development policy. The ammoxidation of aliphatic alcohol process can be divided into aerobic oxidation-amination reaction or dehydrogenation oxidation-amination reaction, according to whether oxygen was supplied in the reaction process. Both the homogeneous and heterogeneous catalytic system studies were conducted to promote the aerobic oxidation-amination reaction, whereas the researches about dehydrogenation oxidation-amination reaction mainly focused on the heterogeneous catalytic system. Herein, the research progress on preparation of aliphatic nitriles through ammoxidation reaction of aliphatic alcohols is reviewed, the advantages and shortcomings of the researches is analyzed and the development direction of the researches on ammoxidation reaction of aliphatic alcohols are prospected.