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Solution conformation of tripeptides by NMR spectroscopy and force-field calculations
Authors:E. Kleinpeter  D. Ströhl  S. Peinze
Affiliation:(1) Institut für Organische Chemie und Strukturanalytik der Universität Potsdam, Am Neuen Palais 10, D-14415 Potsdam, Germany;(2) Institut für Analytik und Umweltchemie der Martin-Luther Universität Halle-Wittenberg, Halle/Saale, Germany
Abstract:The solution conformation of three linear tripeptides Boc-Ala-Val-Val-OMe1, Boc-Ala-Pro-Val-OMe2, and Boc-Ala-(D)Pro-Val-OMe3 was studied by NMR spectroscopy and accompanying force-field calculations. In one case,2, as preferred conformation theepsi-turnall trans conformer was found.
Keywords:Conformational analysis  tripeptides  NMR-spectroscopy
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