Synthesis of imidazo[1,2-c]pyrimidine derivatives from 4-aminopyrimidines,methyl ketones,and halogens

Imidazo1,2-c]pyrimidine derivatives were synthesized from C-substituted 4-aminopyrimidines by the King method. The corresponding 8-bromoimidazo1,2-c]pyrimidines are formed by reaction of 4-aminopyrimidines without substituents in the 5 position with methyl ketones and bromine in a ratio of 112.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 93–94, January, 1975.