Direct separation of drug enantiomers by high-performance liquid chromatography with chiral stationary phases |
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Authors: | A C Mehta |
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Institution: | Department of Pharmacy, General Infirmary, Leeds, Yorkshire, U.K. |
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Abstract: | The development of chiral stationary phases for HPLC has resulted in renewed interest in methods for the separation of drug enantiomers. This paper provides a brief overview of some of the more recent approaches to the direct resolution of drug enantiomers by HPLC with particular emphasis on their quantification in biological fluids. |
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