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Direct separation of drug enantiomers by high-performance liquid chromatography with chiral stationary phases
Authors:A C Mehta
Institution:Department of Pharmacy, General Infirmary, Leeds, Yorkshire, U.K.
Abstract:The development of chiral stationary phases for HPLC has resulted in renewed interest in methods for the separation of drug enantiomers. This paper provides a brief overview of some of the more recent approaches to the direct resolution of drug enantiomers by HPLC with particular emphasis on their quantification in biological fluids.
Keywords:
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