Precision estimates produced by specially-designed ruggedness tests compared with those derived from collaborative trials,in relation to estimation of measurement uncertainty |
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Authors: | Thompson Michael Guffogg Stephen Stangroom Stephen Osborne Paula Key Pauline Wood Roger |
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Affiliation: | School of Biological and Chemical Sciences, Birkbeck College (University of London), Gordon House, 29 Gordon Square, London, UK WC1H 0PP. |
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Abstract: | We have compared the reproducibility precisions provided by collaborative trials with precisions obtained from ruggedness tests specially designed to try to simulate between-laboratory variation. We found that the ruggedness tests underestimated the reproducibility variability consistently for those analytical methods requiring empirical calibration. The ruggedness tests provided on average a precision merely comparable with repeatability precision. This finding has implications for the estimation of uncertainty. |
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