Synthesis and anti-peptic activity of compounds related to the metabolites of sodium 3-ethyl-7-isopropyl-1-azulenesulfonate (KT1-32). |
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Authors: | T Yanagisawa K Kosakai C Izawa T Tomiyama M Yasunami |
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Institution: | Kotobuki Seiyaku Co., Ltd., Nagano, Japan. |
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Abstract: | The metabolites of sodium 3-ethyl-7-isopropyl-1-azulenesulfonate (KT1-32, 1), a candidate as an anti-ulcer drug, and related compounds were synthesized. The effects of the compounds on anti-peptic activity were determined as compared to that of 1. |
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