Synthesis and biological activity of new 2-amino-4-[3-methyl-3-(5,6,7,8-tetrahydro-2-naphthyl)cyclobutyl]thiazole derivatives |
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Authors: | M Koparır A Cansız M Ahmedzade |
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Institution: | (1) Chemistry Department, Faculty of Arts and Sciences, F rat University, Elaz![imath](/content/k5j1678386342114/xlarge305.gif) , 23119, Turkey |
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Abstract: | 2-Amino-4-3-methyl-3-(5,6,7,8-tetrahydro-2-naphthyl)cyclobutyl]thiazole was synthesized by reaction of 1-methyl-1-(5,6,7,8-tetrahydro-2-naphthyl)-3-chloroacetylcyclobutane with thiourea in ethanol, and its subsequent transformations afforded new derivatives which were tested in vitro for antibacterial activity against some bacteria using the disk diffusion technique.__________From Zhurnal Organicheskoi Khimii, Vol. 40, No. 12, 2004, pp. 1861–1865.Original English Text Copyright © 2004 by Kopar r, Cans z, Ahmedzade.The original article was submitted in English. |
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