Application of carbene chemistry in the synthesis of organofluorine compounds |
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Authors: | Xuyong Wang Xi Wang Jianbo Wang |
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Institution: | 1. Institute of Chemical Biology and Nanomedicine, State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, People''s Republic of China;2. Beijing National Laboratory of Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing, 100871, China |
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Abstract: | The methods for the synthesis of fluorine-containing organic compounds are highly demanded due to the importance of those compounds in various fields. On the other hand, carbenes are in general highly reactive species, though which various transformations are possible. Carbene chemistry has been recently explored in the development of new methodologies for the synthesis of organofluorine compounds. This short report summarizes the recent advances in this area. |
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Keywords: | Organofluorine compounds Metal carbene Difluorocarbene Diazo compounds Synthesis |
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