A novel fluorescence probe for cilnidipine assay |
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| Authors: | Shuzhen Tan Jianhui Jiang Guoli Shen Ruqin Yu |
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| Affiliation: | a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, PR China
b Hunan Institute of Science and Technology, Yueyang, Hunan 414000, PR China |
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| Abstract: | A general route for preparation of dye-encapsulated polymer particles via an emulsion polymerization process has been described. 1-Naphthaleneboronic acid (NBA) was encapsulated, the resultant particles were used as a fluorescence probe for cilnidipine assay based on fluorescence quenching. The sensitivity of NBA-encapsulated probe to cilnidipine was largely improved in comparison with that of free NBA. The probe showed a linear response toward cilnidipine over the concentration range of 2.0 × 10−7 to 1.1 × 10−5 mol l−1, with high sensitivity, fast response time, and good selectivity. |
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| Keywords: | 1-Naphthaleneboronic acid Fluorescence probe Cilnidipine Emulsion polymerization Polymer particles |
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