Reaction of arynes with amino acid esters |
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| Authors: | Okuma Kentaro Matsunaga Nahoko Nagahora Noriyoshi Shioji Kosei Yokomori Yoshinobu |
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| Affiliation: | Department of Chemistry, Faculty of Science, Fukuoka University, Fukuoka 814-0180, Japan. kokuma@fukuoka-u.ac.jp |
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| Abstract: | An efficient route to a variety of 2-phenylindolin-3-ones from amino acid methyl esters has been developed. The reaction of amino acid methyl esters with benzyne prepared from 2-(trimethylsilyl)phenyl triflate and CsF gave 2-phenylindolin-3-ones in moderate to good yields. |
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