Synthesis of indanones via solid-supported [2+2+2] cyclotrimerization |
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Authors: | Senaiar Ramesh S Teske Jesse A Young Douglas D Deiters Alexander |
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Institution: | Department of Chemistry, North Carolina State University, Campus Box 8204, Raleigh, North Carolina 27695, USA. |
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Abstract: | A new facile approach toward natural and unnatural indanones has been developed, featuring a solid-supported 2+2+2] cyclotrimerization as the key step. This strategy has been applied to the chemo- and regioselective assembly of indanone arrays and to the total synthesis of a recently isolated indanone marine natural product. |
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