A ratiometric fluorescent probe for the detection of hypochlorous acid in living cells and zebra fish with along wavelength emission |
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| Authors: | Haiqing Xiong Long He Yun Zhang Jingpei Wang Xiangzhi Song Zhaoguang Yang |
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| Institution: | College of Chemistry & Chemical Engineering, Central South University, Changsha 410083, China; Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, Changsha 410083, China |
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| Abstract: | A ratiometric fluorescence probe, NClO, for the rapid and selective detection of HClO had been designed and synthesized based on a 1,8-naphthalimide derivative. Probe NClO displayed a red emission (λmax=615 nm). In the presence of HClO, the solution of probe NClO gave off a strong green fluorescence (λem, max=520 nm) with a rapid response (within seconds). This probe had been applied to image HClO in living cells and zebra fish. |
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| Keywords: | Fluorescent probe Hypochlorous acid Ratiometric Organism Large stokes shift |
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