Amination Reactions of Aryl Halides with Nitrogen‐Containing Reagents Catalyzed by CuI in Ionic Liquid |
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| Authors: | Jin‐Can YAN Li ZHOU Lei WANG |
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| Affiliation: | 1. Department of Chemistry, Huaibei Coal Teachers College, Huaibei, Anhui 235000, China;2. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China;3. Tel.: 0086‐0561‐3802069;4. Fax: 0086‐0561‐3090518 |
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| Abstract: | CuI‐catalyzed coupling reactions of aryl iodides and electron‐deficient aryl bromides with nitrogen‐containing reagents, such as imidazole, benzimidazole, aliphatic primary and secondary amines, aniline, primary and secondary amides, in ionic liquid were developed. The reaction conditions involved the use of [Bmim][BF4] as the solvent, potassium phosphate as the base, and CuI as the catalyst. The CuI and [Bmim][BF4] could be recovered and recycled for five consecutive trials without significant loss of their activity. |
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| Keywords: | amination reaction aryl halide nitrogen‐containing reagent ionic liquid CuI |
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