Action des reactifs de grignard sur les dithioesters : Addition carbophile d'organomagnesiens insatures. synthese de cetones β-ethyleniques |
| |
Authors: | S. Masson M. Saquet A. Thuillier |
| |
Affiliation: | Laboratoires des composés thioorganiques, ERA 391, Université de Caen, 14032 Caen Cedex, France |
| |
Abstract: | Reactions of allyl, benzyl, propargyl and vinyl Grignard reagents with methyl dithioacetate give dithioacetals (or hemidithioacetals) resulting from a carbophilic addition process. Reactions with various allylic organomagnesium compounds always involve an “inversion” of the allylic chain and direct carbophilic addition, rather than initial thiophilic addition followed by [2.3] sigmatropic shift. Three methods for the synthesis of β-unsaturated ketones are described, showing the potential synthetic uses of the reactions of Grignard reagents with dithioesters. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|