4‐Aryl‐2‐ferrocenyl‐ and 2‐Aryl‐4‐ferrocenyl‐2,3‐dihydro‐1,5‐benzothiazepines with Potentially Biological Activities: Synthesis,Characterization, X‐ray Diffraction Studies |
| |
Authors: | Elena I. Klimova Miguel A. Gallardo Vega Jessica J. Sánchez García Marcos Flores‐Alamo José M. Méndez Stivalet |
| |
Affiliation: | Facultad de Química, Universidad Nacional Autónoma de México, Cd. Universitaria, México D.F., México |
| |
Abstract: | A series of novel 4‐aryl‐2‐ferrocenyl‐ and 2‐aryl‐4‐ferrocenyl‐2,3‐dihydro‐1,5‐benzothiazepines 3a , 3b , 3c , 3d , 3e , 3f and 6a , 6b , 6c , 6d , 6e was obtained by the condensation of 1‐aryl‐3‐ferrocenyl‐ and 3‐aryl‐1‐ferrocenyl‐2‐propenones 1a , 1b , 1c , 1d , 1e , 1f and 4a , 4b , 4c , 4d , 4e , respectively, with o‐aminothiophenol in the presence of AcOH and HCl (~64–91%). Their structures were established based on the spectroscopic data and X‐ray diffraction analysis of the compounds 3d , 5a , and 6c . |
| |
Keywords: | |
|
|