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Design,Synthesis, and Biological Screening of Novel Anthranilic Diamides
Authors:Xuewen Hua  Wutao Mao  Zhijin Fan  Xiaotian Ji  Fengyun Li  Guangning Zong  Haibin Song  Kalinina Tatiana  Yury Yu Morzherin  Nataliya P Belskaya  Vasiliy A Bakulev
Institution:1. State Key Laboratory of Elemento‐Organic Chemistry, Nankai University, Tianjin, People's Republic of China;2. Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, People's Republic of China;3. College of Chemistry and Pharmacy Engineering, Nanyang Normal University, Henan, People's Republic of China;4. The Ural Federal University Named after the First President of Russia B. N. Yeltsin, Ekaterinburg, Russia
Abstract:Three series of new anthranilic diamide derivatives containing sulfide, N‐cyanomethylsulfilimine, and N‐cyanomethylsulfoximine groups were designed and synthesized by combining the active substructures of anthranilic diamides and sulfoxaflor. The structures of all newly synthesized compounds were confirmed by IR and 1H/13C‐NMR, and some of them were confirmed by elemental analysis or HRMS too. The synthesized compounds were screened for their insecticidal and fungicidal activities. Bioasssay results indicated that some of the synthesized compounds possessed certain degrees of insecticidal activity against Mythimna separata. However, some compounds exhibited good fungicidal activity against Sclerotinia sclerotiorum.
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