Synthesis and Antifungal Activities of Some New 5,7‐Disubstituted[1,2,4]Triazolo[1,5‐a]Pyrimidin‐6‐one Derivatives |
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| Authors: | Susanta Kumar Borthakur Sukanya Borthakur Debarshi Goswami Paran Boruah Pabitra Kumar Kalita |
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| Affiliation: | 1. Department of Chemistry, Arya Vidyapeeth College, Guwahati, Assam, India;2. Medicinal Aromatic and Economic Plant Division, North East Institute of Science and Technology, Jorhat, India |
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| Abstract: | Synthesis of a new series of [1,2,4]triazolo[1,5‐a]pyrimidin‐6‐one by [4 + 2]cycloaddition reaction of 3‐benzylidineamino[1,2,4]triazole with monophenyl ketene and diphenyl ketene generated in situ from phenylacetyl chloride and diphenylacetyl chloride in the presence of triethylamine is described. The newly synthesized compounds were also tested for antifungal activities against Rhizoctonia solani and Trichoderma sp. |
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