A Facile Three‐Component One‐Pot Synthesis of Some Novel Tricyclic Hetero‐Ring Systems |
| |
Authors: | Sobhi M Gomha Fathy M Abdelrazek |
| |
Institution: | Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt |
| |
Abstract: | A novel, facile, one‐pot, multicomponent reaction for the synthesis of a series of pyrano2,3‐d]1,2,4]triazolo4,3‐a]pyrimidine and pyrano2′,3′:4,5]pyrimido2,1‐b]1,3,5]thiadiazine derivatives has been developed from reaction of 2,4‐dichlorobezaldehyde, malononitrile, and the appropriate active methylene compounds in refluxing dioxane in the presence of chitosan. A plausible mechanism has been proposed for this reaction, and the structure of the newly synthesized compounds was all established on the basis of spectral data (mass, IR, and 1H‐NMR) and elemental analyses. |
| |
Keywords: | |
|
|