Microwave‐assisted Regioselective Synthesis of Novel Bis(azoles) and Bis(azoloazines) |
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| Authors: | Abdullah S Al‐Bogami Ahmed E M Mekky |
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| Institution: | 1. Chemistry Department, Faculty of Science, University of Jeddah, Jeddah, Saudi Arabia;2. Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt |
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| Abstract: | We introduce efficient regioselective synthesis of a series of novel bis(pyrazoles) and bis(isoxazoles) via 1,3‐dipolar cycloaddition reaction under microwave irradiation. Unequivocal structural assignment of the obtained regioisomers was determined utilizing 1H‐13C HMBC NMR techniques as a valuable tool. A comparative study of the aforementioned reactions was carried out under conventional method as well as under microwave irradiation conditions. |
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