Catalytic enantioselective synthesis of adociacetylene B |
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Authors: | Trost Barry M Weiss Andrew H |
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Institution: | Department of Chemistry, Stanford University, Stanford, California 94305-5080, USA. bmtrost@stanford.edu |
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Abstract: | A catalytic enantioselective total synthesis of adociacetylene B (2) in five steps is reported. The efficiency of this synthesis was enabled by an asymmetric zinc alkynylation catalyzed by the proline-derived ligand (1). |
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