Biodegradable microcapsules designed via 'click' chemistry |
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Authors: | De Geest Bruno G Van Camp Wim Du Prez Filip E De Smedt Stefaan C Demeester Jo Hennink Wim E |
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Affiliation: | Department of Pharmaceutics, Utrecht University, 3584 CA Utrecht, The Netherlands. br.degeest@ugent.be |
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Abstract: | Dextrans modified with alkyne and azide groups through hydrolysable carbonate esters form degradable microcapsules after Cu(I) catalysed 'click' reaction between azides and alkynes yielding triazole cross-links. |
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