Nicking enzyme based homogeneous aptasensors for amplification detection of protein |
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| Authors: | Zheng Ai-Xian Wang Jin-Ru Li Juan Song Xiao-Rong Chen Guo-Nan Yang Huang-Hao |
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| Affiliation: | The Key Lab of Analysis and Detection Technology for Food Safety of the MOE, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, PR China. |
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| Abstract: | A simple and highly sensitive homogeneous aptasensor is developed, which relies on nicking enzyme. The sensitivity of this newly proposed aptasensor is about three orders of magnitude higher than that of traditional homogeneous aptasensors. Furthermore, it is capable of detecting target protein in real samples. |
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