On the possibility of regulating the rate of enzymatic destruction of chitosan in an acetic acid solution |
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Authors: | V V Chernova I F Tuktarova E I Kulish |
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Institution: | 1.Bashkir State University,Ufa, Bashkortostan,Russia |
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Abstract: | The enzymatic destruction of chitosan in an acetic acid solution in the presence of sodium chloride and sulfate was considered. It was shown that the addition of these low-molecular electrolytes is accompanied by a tightening of the macromolecular coil, as indicated by a decrease in the α constant in the Mark–Kuhn–Houwink equation and the intrinsic viscosity of chitosan. As a consequence, the chitosan units become less accessible for interaction with the enzyme, and the kinetic parameters of the process (Michaelis constant K M and the maximum rate of enzymatic destruction V max) change accordingly. This suggests that the resistance of this polymer to the enzyme action can be enhanced by introducing low-molecular electrolyte salts in the solution or film coating to suppress the polyelectrolyte swelling of chitosan. |
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