4-Hydroxy-2-quinolones 150*. Efficient synthesis,structure, and biological activities of 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid alkyl amides |
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| Authors: | I. V. Ukrainets N. L. Bereznyakova V. A. Parshikov O. V. Gorokhova |
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| Affiliation: | (1) National University of Pharmacy, Kharkiv, 61002, Ukraine |
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| Abstract: | A simple and efficient method for preparing 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid alkyl amides is proposed. The results of a study of the diuretic activity of the compounds synthesized are reported. *For communication 149 see [1]. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1841-1848, December, 2008. |
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| Keywords: | diuretics 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid amidation X-ray structural analysis |
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