| Effects of Cu~(2+) on characteristic of SV currents |
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| 引用本文： | ZHANG Liping1,2 & YANG Pin1 1. Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education,Institute of Molecular Science,Shanxi University,Taiyuan 030006,China, 2. Institute of Environment Science,Taiyuan University of Science and Technology,Taiyuan 030024,China. Effects of Cu~(2+) on characteristic of SV currents[J]. 中国科学B辑(英文版), 2006, 49(6) |
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| 作者姓名： | ZHANG Liping1 2 & YANG Pin1 1. Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education Institute of Molecular Science Shanxi University Taiyuan 030006 China 2. Institute of Environment Science Taiyuan University of Science and Technology Taiyuan 030024 China |
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| 作者单位： | ZHANG Liping1，2 & YANG Pin1 1. Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education，Institute of Molecular Science，Shanxi University，Taiyuan 030006，China; 2. Institute of Environment Science，Taiyuan University of Science and Technology，Taiyuan 030024，China |
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| 基金项目： | 国家自然科学基金;山西省自然科学基金 |
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| 摘 要： | Applying the patch-clamp technique to vacuoles from Radish we studied the effects of Cu2 on Slow Vacuolar (SV) current’s characteristic. Our results show that Cu2 in bath solution at higher concentration inhibits SV currents and the percentage of inhibition increases with increasing concentration and changes with different voltage. When at lower concentration, Cu2 significantly promotes the SV currents and the promotion ratio decrease with increasing voltage. At the same time, the time constants of activation become lesser after adding Cu2 . These results show that there may be some Cu2 binding sites on SV channels and binding to which can change SV current’s characteristic.
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Effects of Cu2+ on characteristic of SV currents |
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| ZHANG Liping,YANG Pin. Effects of Cu2+ on characteristic of SV currents[J]. Science in China(Chemistry), 2006, 49(6) |
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| Authors: | ZHANG Liping YANG Pin |
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| Abstract: | Applying the patch-clamp technique to vacuoles from Radish we studied the effects of Cu2+ on Slow Vacuolar (SV) current's characteristic. Our results show that Cu2+ in bath solution at higher concentration inhibits SV currents and the percentage of inhibition increases with increasing concentration and changes with different voltage. When at lower concentration, Cu2+ significantly promotes the SV currents and the promotion ratio decrease with increasing voltage. At the same time, the time constants of activation become lesser after adding Cu2+. These results show that there may be some Cu2+ binding sites on SV channels and binding to which can change SV current's characteristic. |
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| Keywords: | the patch-clamp technique vacuolar Cu2 SV channel |
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