Preparation of magnetite nanocrystals with surface reactive moieties by one-pot reaction |
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Authors: | Hu Fengqin Li Zhen Tu Chifeng Gao Mingyuan |
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Institution: | Key Laboratory of Colloid, Interface Science and Chemical Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Zhong Guan Cun, Bei Yi Jie 2, Beijing 100080, China. |
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Abstract: | By one-pot reaction, biocompatible magnetite nanocrystals with surface reactive moieties were prepared through the thermal decomposition of Fe(acac)(3) in 2-pyrrolidone using alpha,omega-dicarboxyl-terminated poly(ethylene glycol) as surface capping molecule. The successful conjugation between the magnetite nanocrystals and 9-amino acridine on the one hand demonstrates the existence of free carboxylic groups from PEG binding on the particle surface, on the other hand may also lead to a new type of magneto-optical materials as well as magneto-drugs. |
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