两种含杂环的氨基萘醌化合物的合成

以2,3-二氯-1,4-萘醌为主要原料,分别与吗啡啉和糠胺在一定条件下反应生成2种含杂环的氨基萘醌类化合物。2,3-二氯-1,4-萘醌与吗啡啉及2,3-二氯-1,4-萘醌与糠胺物质的量比均为1∶2,反应温度为60℃,溶剂为乙醇。2,3-二氯-1,4-萘醌与吗啡啉反应时间为1 h,产物2-氯-3-吗啡啉基萘-1,4-二酮(a)收率为93.5%;2,3-二氯-1,4-萘醌与糠胺反应时间为4 h,产物N~2,N~3-二(2-呋喃甲基)-1,4-二((2-呋喃甲基)亚胺)-1,4-二氢化萘-2,3-二氯化铵(d)收率为46.7%。对产物进行IR、Uv、MS和H-NMR等分析表征。

Synthesis of Two Kinds of Amino Naphthoquinones of Containing Heterocyclic

The experiments had used 2,3-dichloro-1,4-naphthoquinone as the main raw material under certain conditions, so as to react with morpholino and furfurylamine reactrespectively to obtain amino naphthoquinone compounds containing heterocyclic. The reaction temperature is 60℃. The solvent is ethanol. The molar ratio of 2,3-dichloro-1,4-naphthoquinone to morpholine and 2,3-dichloro-1,4-naphthoquinone to furfurylamine were 1∶2 respectively. The yield of 2-chloro-3-morpholinonaphthalene-1,4-dione attain to 93.5%with reaction time 1 hour. The yield of N2,N3-bis(furan-2-ylmethyl)-1,4-bis((furan-2-ylmethyl)imino)-1,4-dihydronaphthalene-2,3- diaminium chloride attain to 46.7%with reaction time 4 hours. IR, UV, MS and HNMR have been determined to characterize the structure of the products.