金属-有机骨架ZIF-8@Fe_3O_4复合物的制备及其用于磁固相萃取对水中内分泌干扰物的测定

制备了金属-有机骨架ZIF-8@Fe_3O_4复合物,考察了ZIF-8生长次数、萃取时间、离子强度、pH值、解吸溶剂和解吸时间等对萃取和解吸的影响,并通过磁固相萃取结合高效液相色谱法将其成功用于水中双酚A、雌酚酮、壬基酚和辛基酚4种内分泌干扰物的检测。该方法对上述4种物质的线性范围为1.0～1 000μg/L,检出限为0.42～0.81μg/L,富集因子为61～144,日内和日间精密度分别为2.1%～4.3%和3.5%～5.8%。

Fabrication of a Metal-Organic Frameworks ZIF-8@Fe3O4 Composite and Its Magnetic Solid Phase Extraction of Endocrine Disrupting Chemicals in Water

A metal-organic framework ZIF-8@Fe 3O 4 composite was synthesized for the extraction of endocrine disrupting chemicals (EDCs ) in water samples by magnetic solid phase extraction (MSPE ).Effects of ZIF-8 growth cycles,extraction time,ionic strength,pH,desorption solvent and desorption time on MSPE were investigated.The developed MSPE combined with high performance liquid chromatography was successfully applied in the detection of 4 endocrine disrupting chemicals (EDCs ),i.e.bisphenol A,nonyl phenol,octyl phenol and estrone in water samples.Under the optimized conditions,there existed linear relationships for the 4 analytes in the range of 1.0- 1 000 μg/L,with the detection limits ( S/N =3 ) of 0.42-0.81 μg/L and the enhancement factors of 61-144.The relative standard deviations (RSDs ) for inter-day ( n =6 ) and intra-day ( n =3 ) were 2.1 %-4.3 % and 3.5 %-5.8 %,respectively.