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Development of an end-game strategy towards apoptolidin: a sequential Suzuki coupling approach
Authors:Bohan Jin
Institution:Department of Chemistry, Texas A&M University, P.O. Box 30012, College Station, TX 77842-3012, USA
Abstract:An end-game strategy towards the synthesis of apoptolidin has been demonstrated in a model study, in which the C(1)-C(15) fragment was successfully assembled using three consecutive Suzuki coupling reactions.
Keywords:Natural product synthesis  Trienoate  Cross-coupling
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