Preparation of novel pyrrol-2-one derivatives via an effective synthesis of new oxazole scaffold |
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| Authors: | ?brahim Evren Kibriz Mustafa Saçmaci Ertan ?ahin ?smail Yildirim |
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| Institution: | 1. Department of Chemistry, Faculty of Arts and Sciences, Bozok University, 66200 Yozgat, Turkey;2. Department of Chemistry, Faculty of Sciences, Atatürk University, 25240 Erzurum, Turkey;3. Department of Chemistry, Faculty of Sciences, Erciyes University, 38039 Kayseri, Turkey |
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| Abstract: | A convenient procedure for the preparation of oxazole and pyrrole derivatives is described. 2-Amino-1,3-oxazol-2-ones 3a,b were first synthesized from the cyclocondensation reactions of cyanamide (2) with 4-ethoxycarbonyl-5-aryl-2,3-furandione 1a,b, and then new pyrrol-2-ones 5 were synthesized from the reaction of the compounds 3 with various aromatic amines 4. |
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| Keywords: | Furan-2 3-dione Cyanamide Oxazole Pyrrole Cycloaddition |
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