The Synthesis of Novel Iodinated Iminodiacetic Acid Analogues as Hepatobiliary Imaging Agents |
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| Authors: | Jasmina S Brbori? Sote Vladimirov Mirjana S Jovanovi? and Nikola Dogovi? |
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| Institution: | (1) Department of Biosciences and Informatics, Keio University, 3-14-1, Hiyoshi, Yokohama 223-8522, Japan;(2) Department of Materials Science, Tottori University, 4-101, Koyama-Minami, Tottori 680-8552, Japan;(3) Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Tokyo 153-8904, Japan; |
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| Abstract: | The synthesis and characterization of N-2-4-iodo-2,6-bis(1-methylethyl)phenyl]amino]-2-oxoethyl]-N-(carboxymethyl)glycine and N-2-(4-iodo-2,6-diethylphenyl)amino]-2-oxoethyl]-N-(carboxymethyl)glycine is presented, as well as a modified and improved synthesis of N-2-(2,4-diiodo-6-methylphenyl)amino]-2-oxoethyl]-N-(carboxymethyl)glycine. These compounds are new agents for hepatobiliary imaging. |
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