Pyrrolidine-thiourea as a bifunctional organocatalyst: highly enantioselective Michael addition of cyclohexanone to nitroolefins |
| |
| Authors: | Cao Chun-Li Ye Meng-Chun Sun Xiu-Li Tang Yong |
| |
| Affiliation: | The State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, China. |
| |
| Abstract: | [reaction: see text] Asymmetric Michael additions of cyclohexanone to both aryl and alkyl nitroolefins in the presence of 20 mol % of organocatalyst 2b and 10 mol % of n-butyric acid afford adducts 5 with high diastereoselectivities and enantioselectivities. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
